Hi everyone. I'm sorry but I just can't seem to get the relationship between these 2 right.
I've heard that human leukocyte antigen are antigens that help the immune system to distinguish proteins of an individual against those of pathogens. If the transplant HLA doesn't match, it provokes an immune response and is rejected.
I've also heard that antigens define unique tissue types of individuals based on their genetics and if the tissue types of a transplant doesn't match the recipient's tissue type it also provokes an immune response and rejection.
So does that mean HLA shows tissue types as well as defining the protein, and if not why do they both provoke an immune response please.
Thank you for answering, I'm sorry for my stupidity