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help with cell question in biology?

Mature red blood cells are anucleate cells, that is, they do not have nuclei. They are, however, filled with hemoglobin for binding oxygen. Do you suppose that these cells are anucleate throughout life or did they at one time have nuclei?

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Actually, red blood cells have their nuclei when they're still in the bone marrow. Once they leave, they will no longer have their nuclei.

Reference: from our Z001 class